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Description
The Deeper Genome: Why There Is More to the Human Genome Than Meets the EyeOver a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought just over 20,000, the same sort of number as a fruit fly or worm. What's more,
Over a decade ago, as the Human Genome Project completed its mapping of the entire human genome, hopes ran high that we would rapidly be able to use our knowledge of human genes to tackle many inherited diseases, and understand what makes us unique among animals. But things didn't turn out that way. For a start, we turned out to have far fewer genes than originally thought -- just over 20,000, the same sort of number as a fruit fly or worm. What's more, the proportion of DNA consisting of genes coding for proteins was a mere 2%. So, was the rest of the genome accumulated 'junk'? Things have changed since those early heady days of the Human Genome Project. But the emerging picture is if anything far more exciting. In this book, John Parrington explains the key features that are coming to light - some, such as the results of the international ENCODE programme, still much debated and controversial in their scope. He gives an outline of the deeper genome, involving layers of regulatory elements controlling and coordinating the switching on and off of genes; the impact of its 3D geometry; the discovery of a variety of new RNAs playing critical roles; the epigenetic changes influenced by the environment and life experiences that can make identical twins different and be passed on to the next generation; and the clues coming out of comparisons with the genomes of Neanderthals as well as that of chimps about the development of our species. We are learning more about ourselves, and about the genetic aspects of many diseases. But in its complexity, flexibility, and ability to respond to environmental cues, the human genome is proving to be far more subtle than we ever imagined.Binding Type: Paperback
Publisher: Oxford University Press, USA
Published: 10/24/2017
ISBN: 9780198813095
Pages: 400
Weight: 0.60lbs
Size: 7.60h x 5.00w x 0.90d
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4.3 ★★★★★
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Product Reviews
★★★★★ 5
Didn’t last long but they had a blast
Color: Octopus Purple & Blue
These octopus squeak and crinkle dog toys were a hit with my two pitties. I had about two hours of quiet out of them before they started ripping them apart to get the squeakers. For this reason, you will want to watch your dog if they are a larger breed. They were super cute when they arrived and are a fantastic price for the fun my dogs had with them. I will definitely order them again.
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Reviewed in the United States on February 8, 2026
★★★★★ 5
Great value and quality!
Cute and My dog loved them! Pretty durable.
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Reviewed in the United States on June 1, 2026
★★★★★ 4
Cute for a puppy or small dog- not meant for chewers
Color: Octopus Purple & Blue, Color: Octopus Purple & Blue
I bought this cute squid two-pack as Christmas toys for two dogs, and they’re absolutely adorable. The colors are bright and fun, and the crinkle sound inside is very appealing especially to the puppy I was buying for.
They are a little smaller than I expected, but I added a photo with my hand in it for size reference. The size ended up being perfect for our 12-week-old Irish Setter/Golden Retriever mix. He loves grabbing the tentacles and flinging it around. It’s easy for him to hold, shake, and carry, which makes it a great puppy toy.
I also have a German Shorthaired Pointer, and it’s definitely not big enough or sturdy enough for her, she doesn’t really play with it. But for a puppy or small dog, it’s ideal.
The Tupac is ideal, but losing one star just for durability and size.
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Reviewed in the United States on February 21, 2026
★★★★★ 5
Lasted longer than I expected! But Still going...
Color: Octopus Yellow & Green
My dog was hesitant at first, which was strange because he loves the squeaker toys. would smell them and then walk away (I think it had a manufacturing smell) but after a few hours of airing out the fight (Playing) was on!
Lasted longer than I expected! the squeak was gone from one of them but somehow, he managed to get it working again. normally he would chew the guts out to get to the squeaking piece, but they are surprisingly both still in tacked!
and also, he refuses to share with his big brother even though he has two of them!
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Reviewed in the United States on December 30, 2025
★★★★★ 3
Another one bites the dust!
Color: Octopus Purple & Blue
Good toy, but nothing spectacular. Took my 10 month old girl less than a day to kill the squeaker lol. Item is still intact meaning its not shredded but once squeaker dies she's pretty much done with it.
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Reviewed in the United States on December 20, 2025