FGF-12 Protein, Mouse/Rat
SKU: 54949428646

FGF-12 Protein, Mouse/Rat

Sale price$124.20 Regular price$138.00
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Description

FGF-12 Protein, Mouse/RatProduct Specification Species Mouse Synonyms Fibroblast growth factor 12, FGF 12, Fibroblast growth factor homologous factor 1 (FHF 1), Myocyte activating factor Accession P61329 Amino Acid Sequence Met1 Thr243 Expression System E. coli Molecular Weight 27kDa (Reducing) Purity 95% by SDS PAGE Endotoxin <0. 1EU g Conjugation Unconjugated Tag No Tag Physical Appearance Lyophilized Powder Storage Buffer 20mM Tris, 500mM NaCl, pH8. 0 Reconstitution

Product Specification


Species Mouse
Synonyms Fibroblast growth factor 12, FGF-12, Fibroblast growth factor homologous factor 1 (FHF-1), Myocyte-activating factor
Accession P61329
Amino Acid Sequence Met1-Thr243
Expression System E.coli
Molecular Weight

27kDa (Reducing)

Purity >95% by SDS-PAGE
Endotoxin <0.1EU/μg
Conjugation Unconjugated
Tag No Tag
Physical Appearance Lyophilized Powder
Storage Buffer 20mM Tris, 500mM NaCl, pH8.0
Reconstitution

Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

Stability & Storage · 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
Reference

Wiley Interdiscip Rev Dev Biol. 2015 May-Jun;4(3):215-66. Epub 2015 Mar 13.
Cell Commun Signal. 2022 Nov 21;20(1):182.

Background

Members of the FGF family function in the earliest stages of embryonic development and during organogenesis to maintain progenitor cells and mediate their growth, differentiation, survival, and patterning..Among the FGF proteins, the least characterized superfamily is the group of fibroblast growth factor homologous factors (FHFs). The fibroblast growth factor (FGF) family includes 22 genes found in humans that share sequence and structural similarity. FGFs fall into three major groups: canonical FGFs (comprising subfamilies 1, 4, 7, 8 and 9), endocrine FGFs, referred to as the FGF19 subfamily, and fibroblast growth factor homologous factors (FHFs), until recently considered intracellular FGFs, termed the FGF11 subfamily.

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SKU: 54949428646

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4.9 ★★★★★
Based on 2038 reviews
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Verified Purchase
Greg B.
Massapequa, US
★★★★★ 5
Durable and a favorite toy
My 7 month old Black Lab loves this bone. She is a chewer and has gone to town on the three ends. They are roughed up a bit but holding up better than expected. Highly recommend for dogs that love to chew.
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Reviewed in the United States on June 6, 2026
L
Verified Purchase
Lea
Port Orchard, US
★★★★★ 5
Perfect for aggressive chewers
I have a 2 year old pittie and she chows thru bones in minutes, even those reviewed as "long lasting". This thing is still going strong after 9 months. She was not initially interested, had to spread peanut butter on one end, one time, and now it is her go-to chew toy. Looks a little mangled after all this time but she's not even 75% thru it. Highly recommend, no stomach issues.
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Reviewed in the United States on June 7, 2026
S
Verified Purchase
Sarah Brannan
Waukegan, US
★★★★★ 5
Great, durable bone
My dog loves this bone! It’s super durable and has lasted a few months. Keeps my golden busy! Definitely will buy again.
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Reviewed in the United States on June 9, 2026
V
Verified Purchase
Veronica-Marie Landolfi
Fort Morgan, US
★★★★★ 5
Best long-lasting dog chew
If you want something to occupy your dog that's harmless, this is the one. He doesn't have to chase it, so it doesn't get lost under the cabinets, and he's been chewing it for hours and barely made a mark on it. When he's chewing on this, he's not whining or asking to sit on my lap, and he can stay nearby as he enjoys this toy.
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Reviewed in the United States on June 12, 2026
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Verified Purchase
W&E
Chelsea, US
★★★★★ 4
Not perfect for every dog, but still worth a shot
I bought the bacon-flavored Benebone with high hopes after reading the reviews. Our 45lb mutt loves to chew on bones (and thankfully that's ALL she loves to chew on!) but we've had trouble finding anything that she can't destroy in one sitting. We've heard that antlers are the longest lasting but can be damaging to the dog's teeth, so we wanted to try something with a little less potential for disaster. The Benebone wishbone fared okay. I do have to say that she loved the bone, as did our 14lb schnoodle. The first day she had it, they took turns gnawing on it for hours. Unfortunately, the large one's jaws are quite strong, and so by the end of day 1 there were some pretty significant teething marks on each of the ends, and it was starting to look pretty gnarly. I put it up for a little bit, but they've had other nylon bones that looked worse so I gave it back to them the next day. On day 2, the little one was chewing on it so vigorously (and I think the bone was gnarly enough) that her gums started bleeding. I noticed the blood on the bone so I took it away again. On day 3, I gave the bone back to the large one to chew on. It wasn't too long, though, until I was hearing some pretty loud snaps and I found that the large pup was actually starting to get larger pieces off of the ends of the wishbone. This had me worried, so I threw the wishbone away. Relative to other chew toys that the large one likes (she'll only chew on bones and edibles, for some reason - nothing with any sort of rubbery material), this did actually have a decent life span, but we're still looking for something better. I give the product 3 stars because the dogs clearly loved the bone, and I'm sure that it's perfect for some dogs. For example, if it was just our schnoodle chewing on it, it would have lasted much longer and I would probably be posting a 5-star review here. In the end, though, we did buy the wishbone for the larger dog, and it failed to hold up for her - for the price, I would have wanted something that lasts longer - hence the two star deduction. UPDATE 8/10/2014: Not long after I posted this review, Benebone contacted me in the comments to offer a refund and hinted at the potential for a larger bone sometime in the future. I sent in our order number and they processed the refund quickly. I've added back an extra star, because Benebone's stellar customer service has made the product worth the try. I would definitely do business with Benebone again, and I'm looking forward to trying (or rather, having my pup try) a larger version of the bone if/when it surfaces!
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Reviewed in the United States on August 7, 2014

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